Stem Cell Therapy for Systemic Scleroderma

Systemic Scleroderma (SSc) is the tightening and hardening condition of the skin and CT, which causes different complications in the body. The traditional treatments of the disease focus on the symptomatic management of the disease. However, Stem Cell Therapy and Mesenchymal Stem Cells can help with the root cause of the condition and disease.

Scleroderma belongs to the category of rare disorders that cause the skin and connective tissues to harden and tighten.

Scleroderma is more frequent in women than in males, and it usually strikes between the patients in ages of 30-50. While there is no cure for scleroderma, several treatments can help manage symptoms and improve quality of life.

Scleroderma comes in a variety of forms. SSc affects the skin only in some persons. However, in other patients, it affects structures other than the skin in many patients, including blood vessels, various internal organs, and the human digestive tract. The signs and symptoms differ depending on the kind or type of Scleroderma.

Scleroderma is caused by an excessive amount of collagen being produced and accumulated in the body's tissues. Collagen is a fibrous protein found in the connective tissues of the body, particularly the skin.

Doctors are not sure what triggers aberrant collagen creation, but it appears that the immune system plays a significant role. Scleroderma is most commonly accompanied by a mix of causes, such as environmental triggers, immune system issues, and genetics.

Several combined factors appear to influence the risk of developing Scleroderma:

Genetics: gene variations

Environmental triggers: exposure to certain medications, viruses, bacteria, or drugs

Immune system problems – an autoimmune disease that occurs because the body's immune system begins attacking connective tissues.

The signs and symptoms of Scleroderma differ depending on which regions of your body are influenced:

Skin: causes patches of skin to harden and stiffen. These patches can be round or linear in shape.

Fingers or toes: Raynaud's disease, which causes the contraction of the small blood vessels in your toes and fingers in response to emotional disturbances or cold.

Digestive system: Heartburn, difficulty swallowing, cramps, constipation, bloating, or diarrhea.

Damage to Heart, kidneys or lungs

THE TREATMENT JOURNEY

Medications

No treatment can cure or stop Scleroderma's overproduction of collagen. However, several drugs are available to help manage and prevent scleroderma complications and symptoms.

Your doctor may, for example, prescribe drugs to:

Slow down or treat skin changes – Steroid creams

Cause vasodilation

Suppress the immune system

Reduce symptoms associated with the digestive system

Prevent infections

Relieve pain

Therapies

Occupational or Physical therapists can help you:

Manage pain

Improve your mobility and strength

Maintain independence with ADLs and IADLs

Home and lifestyle remedies

You can take several steps for managing your symptoms of Scleroderma as:

Stay active

Protect your skin

Cessation of smoking

Manage heartburn

Protect yourself from the weather transitions and cold

MSCs are multipotent adult progenitor cells that were first discovered in the bone marrow. Because of their numerous trophic and synergistic effects qualities, Mesenchymal Stem Cells (MSCs) are a promising therapeutic approach. MSCs have immunomodulatory, anti-fibrotic, and angiogenic properties that could be useful in treating this disease by affecting various abnormally dysregulated processes.

The Stem Cell Therapy (SCT) at the Renue Centre is a holistic approach to treating Systemic Scleroderma.

Your Renue Journey does not end after your last day of SCT. We follow up with you to assert your progress, following four phases:

The treatment for Systemic Scleroderma with Stem Cells consists of four phases:

Pre-treatment: clinical evaluation, lab test results, and other diagnostic procedures.

You will take our Renue Epigenetic Test powered by TruDiagnostics that will assert your biological age and other important health markers. Your TruDiagnostics test is part of the Renue Difference. It provides your doctor with critical information about your health and your true age (biological vs chronological).

After the epigenetic test and we have received all your medical records, your Patient Advisor will assist you in planning your travel to Puerto Vallarta.

Treatment day: The route of administration of Stem Cells can be intra-arterial, intranasal, and intravenous. Stem Cells transplantation can range from 1 x 106 – 8 x 106 cells. The dosage of the stem cells also depends upon the severity and type of the disease, which is customizable.

30, 60 & 90 days follow up: Systemic Scleroderma symptoms clinical evaluation, flare-up frequency, and lab test results.

6 months after treatment: Systemic Scleroderma symptoms clinical evaluation, flare-up frequency, lab test results, X-ray report, and review of the diagnostic criteria.

The effectiveness of Stem Cell Treatment can improve all your symptoms, causing a considerable impact on your quality of life and daily activities.

As part of The Renue Difference, you will receive three Hyperbaric Chamber sessions that greatly improve SCT efficacy and stimulate the body cells to combat Systemic Scleroderma. These sessions comprise three days: one day before treatment, after treatment, and on the day of treatment.

According to results, clinical outcomes, and pre-and post-treatment observations, SCT has been shown to help

reduce Systemic Scleroderma progression

speed up tissue repair

regrow and repair tissues after six months

After the SCT procedure, an MRI test depicts the further need for the treatment at a specific body site.

Talk to our Patient Advisor to know more about SCT at The Renue Medical Centre.

Increased life expectancy

Improved life quality

Fewer levels of stress, fatigue, and health

FREQUENT QUESTIONS

The most frequent or common risk factors of SCT can be:

Lethargy and fatigue

Bleeding from the site of injection

Fever

Painful injection area /site

Allergic reactions

When patients exhibit adverse effects, cautious care is usually recommended. Over-the-counter drugs can help reduce negative effects in cases of infections and inflammation. Pre-operative care and patient records are very important in controlling and reducing risk factors.

The Stem Cell Therapy is a new and promising method of treating Systemic Scleroderma. It has the potential to be more effective than previous methods and also carries less risk. At present, stem cell technology is still in the developmental stage, but rapid developments and advances indicate its potential uses in direct treatments of Systemic Scleroderma.

The benefits and effects of Stem Cell Therapy depend on several factors: the patient's health condition, underlying issues, lifestyle, and others.

To assess your expected results, we would like to know more about you.

A medical advisor will talk to you about your diagnosis and treatment options and collect information for the attending physician; they can answer all your initial questions:

Will the therapy work for my case?

What does the treatment involve? Is it painful?

Is it expensive? How much does it cost?